Chagas Disease (African Trypanosomiasis)

Chagas disease is caused by infection with the Trypanosoma cruzi parasite, and is one of the leading causes of heart failure in endemic regions of Latin America.

It is estimated to have infected over 10 million people, and nearly 30 % of chronic Chagas patients eventually develop cardiac complications and heart disease. The existing treatments for Chagas disease have limited efficacy against the chronic stage of the disease, and can cause severe side effects.

By Photo Credit:Content Providers(s): CDC/Dr. Myron G. Schultz [Public domain], via Wikimedia Commons
By Photo Credit:Content Providers(s): CDC/Dr. Myron G. Schultz [Public domain], via Wikimedia Commons
  • FAH/Pande Group researcher Paul Novick has applied ligand-based methods to Chagas disease

    FAH/Pande Group researcher Paul Novick has applied ligand-based methods to Chagas disease and in collaboration with the SPARK project (UCSF) and the McKerrow Lab (UCSF) has started to test the…

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  • Pilot project on Chagas Disease

    We started a pilot project on Chagas Disease.

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